TEL: +86 571 56623320 EMAIL: [email protected]
Product Name Anti-Claudin 4/Cy5 Chinese Name Cy5标记的紧密连接蛋白4抗体 Alias Claudin4; CLDN 4; CLDN4; Clostridium perfringens enterotoxin receptor; Clostridium perfringens enterotoxin receptor 1; CPE R; CPE receptor; CPER; CPETR 1; CPETR; CPETR1; hCPE R; WBSCR8; Williams Beuren syndrome chromosome region 8 protein; Claudin-4; CLD4_HUMAN; Clostridium perfringens enterotoxin receptor; CPE-R; CPE-receptor. Research Area Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species Human, Rat, (predicted: Mouse, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 23kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human CLDN4 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
Claudin 1-8 proteins are a family of transmembrane proteins associated with tight junctions. Tight junctions are specialized regions of cell to cell contact made up of network of strands that act as a molecular gasket for preventing the leakage of ions, water etc. between cells. They are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Different tissues exhibit different Claudin composition.
Subunit:
Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3. Interacts with EPHA2; phosphorylates CLDN4 and may regulate tight junctions.
Subcellular Location:
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
Similarity:
Belongs to the claudin family.
Database links:Entrez Gene: 1364 Human
Entrez Gene: 12740 Mouse
Omim: 602909 Human
SwissProt: O14493 Human
SwissProt: O35054 Mouse
Unigene: 647036 Human
Unigene: 699253 Human
Unigene: 7339 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Username | Quantity | bought time |
He*** | 1 | 2024-08-05 |
Ja*** | 2 | 2024-05-26 |
Um*** | 1 | 2024-04-21 |
Ad*** | 2 | 2024-03-06 |
Ya*** | 2 | 2024-01-24 |
Scan Wechat Qrcode
Scan Whatsapp Qrcode