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Rabbit Anti-Claudin 4/Cy5 Conjugated antibody
Rabbit Anti-Claudin 4/Cy5 Conjugated antibody
Claudin4; CLDN 4; CLDN4; Clostridium perfringens enterotoxin receptor; Clostridium perfringens enterotoxin receptor 1; CPE R; CPE receptor; CPER; CPETR 1; CPETR; CPETR1; hCPE R; WBSCR8; Williams Beuren syndrome chromosome region 8 protein; Claudin-4; CLD4
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  • NO.:SL2790R-Cy5
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Human,Rat,(predicted: Mouse,Chicken,Dog,Pig,Cow,Horse,Rabbit,Sheep,)
    Applications:IF
    concentration:1mg/ml
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Product Name Anti-Claudin 4/Cy5
Chinese Name Cy5标记的紧密连接蛋白4抗体
Alias Claudin4; CLDN 4; CLDN4; Clostridium perfringens enterotoxin receptor; Clostridium perfringens enterotoxin receptor 1; CPE R; CPE receptor; CPER; CPETR 1; CPETR; CPETR1; hCPE R; WBSCR8; Williams Beuren syndrome chromosome region 8 protein; Claudin-4; CLD4_HUMAN; Clostridium perfringens enterotoxin receptor; CPE-R; CPE-receptor.  
Research Area Cell biology  immunology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human, Rat,  (predicted: Mouse, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 23kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human CLDN4
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
Claudin 1-8 proteins are a family of transmembrane proteins associated with tight junctions. Tight junctions are specialized regions of cell to cell contact made up of network of strands that act as a molecular gasket for preventing the leakage of ions, water etc. between cells. They are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Different tissues exhibit different Claudin composition.

Subunit:
Directly interacts with TJP1/ZO-1, TJP2/ZO-2 and TJP3/ZO-3. Interacts with EPHA2; phosphorylates CLDN4 and may regulate tight junctions.

Subcellular Location:
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.

Similarity:
Belongs to the claudin family.

Database links:

Entrez Gene: 1364 Human

Entrez Gene: 12740 Mouse

Omim: 602909 Human

SwissProt: O14493 Human

SwissProt: O35054 Mouse

Unigene: 647036 Human

Unigene: 699253 Human

Unigene: 7339 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Partial purchase records(bought amounts latest6)

UsernameQuantitybought time
He***12024-08-05
Ja***22024-05-26
Um***12024-04-21
Ad***22024-03-06
Ya***22024-01-24
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