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Product Name Anti-TRIP1/Cy5 Chinese Name Cy5标记的甲状腺受体相互作用蛋白1抗体 Alias 26S protease regulatory subunit 8; Cim3; MSUG1 protein; p45 antibody p45/SUG; Proteasome (prosome macropain) 26S subunit ATPase 5; Proteasome 26S ATPase subunit 5; Proteasome 26S subunit ATPase 5; Proteasome prosome macropain 26S subunit ATPase 5; Proteasome subunit p45; PSMC 5; PSMC5; Rpt6; S8 antibody SUG 1; SUG1; Tat binding protein homolog 10; TBP 10; TBP10; Thyroid hormone receptor interacting protein 1; Thyroid receptor interactor 1; TRIP 1; TRIP1; TRIP1(SUG1). Research Area Cell biology The cell membrane受体 Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Rabbit, ) Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 45kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human TRIP1/PSMC5 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
Human SUG1 (also known as p45, Rpt6, Cim3 and PSMC5) is a component of the 19S regulatory subunit of the 26S proteosome complex. It is one of the AAA ATPas found in the 19S regulatory complex that is thought to participate in the unfolding of ubiquitinated proteins in an ATP dependent manner. It has also been shown to directly interact with the nucleotide excision repair protein XPB.
Function:
The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.
Subunit:
Interacts, in vitro, with the thyroid hormone receptor (in a thyroid hormone T3-dependent manner) and with retinoid X receptor (RXR) (By similarity). Interacts with NDC80. Interacts with PAAF1.
Subcellular Location:
Cytoplasm (Potential). Nucleus (Potential).
Similarity:
Belongs to the AAA ATPase family.
Database links:
UniProtKB/Swiss-Prot: P62195.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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