TEL: +86 571 56623320 EMAIL: [email protected]
Product Name Anti-S100 alpha 2/Cy5 Chinese Name Cy5标记的S100A2抗体 Alias S100 calcium binding protein A2; CAN19; MGC111539; Protein S 100L; Protein S-100L; Protein S100 A2; Protein S100-A2; Protein S100L; S100 A2; S100 calcium-binding protein A2; S100A2; S100L; S10A2_HUMAN. Research Area Tumour Cell biology Signal transduction Cyclin Binding protein Cell differentiation Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Goat, Cat, ,lizard) Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 11kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human S100 alpha 2 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
The protein encoded by this gene is a member of the S100family of proteins containing 2 EF-hand calcium-binding motifs.S100 proteins are localized in the cytoplasm and/or nucleus of awide range of cells, and involved in the regulation of a number ofcellular processes such as cell cycle progression anddifferentiation. S100 genes include at least 13 members which arelocated as a cluster on chromosome 1q21. This protein may have atumor suppressor function. Chromosomal rearrangements and alteredexpression of this gene have been implicated in breast cancer.
Function:
May act as a modulator against excess calciumaccumulation in normal human mammary epithelial cells. May alsoplay a role in suppressing tumor cell growth.
Subunit:
Homodimer. Interacts with FKBP4.
Tissue Specificity:
A subset of epithelial cells including normalhuman mammary epithelial cells and keratinocytes.
Similarity:
Belongs to the S-100 family
Contains 2 EF-hand domains.
Database links:
UniProtKB/Swiss-Prot: P29034.3
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Scan Wechat Qrcode
Scan Whatsapp Qrcode