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Rabbit Anti-VAT1L/Cy5 Conjugated antibody
Rabbit Anti-VAT1L/Cy5 Conjugated antibody
Probable oxidoreductase KIAA1576; Synaptic vesicle membrane protein VAT 1 homolog like; Synaptic vesicle membrane protein VAT-1 homolog-like; VAT 1L; VAT1L; VAT1L_HUMAN; Vesicle amine transport protein 1 homolog (T. californica) like.
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Details

Product Name Anti-VAT1L/Cy5
Chinese Name Cy5标记的囊泡胺Transporter1家族蛋白抗体
Alias Probable oxidoreductase KIAA1576; Synaptic vesicle membrane protein VAT 1 homolog like; Synaptic vesicle membrane protein VAT-1 homolog-like; VAT 1L; VAT1L; VAT1L_HUMAN; Vesicle amine transport protein 1 homolog (T. californica) like.  
Research Area Cell biology  immunology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Rat,  (predicted: Human, Mouse, Chicken, Dog, Pig, Horse, Sheep, )
Applications IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 46kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human KIAA1576/VAT1L
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier. The KIAA1576 gene product has been provisionally designated KIAA1576 pending further characterization.

Similarity:
Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

Database links:

Entrez Gene: 57687 Human

SwissProt: Q9HCJ6 Human

Unigene: 461405 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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