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Product Name Anti-CACNG6/Cy5.5 Chinese Name Cy5.5标记的神经元电压门控钙通道γ6抗体 Alias calcium channel voltage dependent gamma subunit 6; Neuronal voltage gated calcium channel gamma 6 subunit; Voltage-dependent calcium channel gamma-6 subunit. Research Area Tumour Cell biology Neurobiology Signal transduction Channel protein Immunogen Species Rabbit Clonality Polyclonal React Species Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 28kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human CACNG6 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
Voltage-dependent calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of two known gamma subunit proteins. This particular gamma subunit is an integral membrane protein that is thought to stabilize the calcium channel in an inactive (closed) state. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members that function as transmembrane AMPA receptor regulatory proteins (TARPs). Alternative splicing results in multiple transcript variants. Variants in this gene have been associated with aspirin-intolerant asthma. [provided by RefSeq, Dec 2010]
Function:
Thought to stabilize the calcium channel in an inactivated (closed) state.
Subunit:
The L-type calcium channel is composed of five subunits: alpha-1, alpha-2/delta, beta and gamma.
Subcellular Location:
Plasma membrane
Similarity:
Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
Database links:Entrez Gene: 59285 Human
Entrez Gene: 54378 Mouse
Omim: 606898 Human
SwissProt: Q9BXT2 Human
SwissProt: Q8VHW3 Mouse
Unigene: 91033 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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