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Rabbit Anti-NOTO/Cy5.5 Conjugated antibody
Rabbit Anti-NOTO/Cy5.5 Conjugated antibody
floating head homolog;Homeobox protein notochord;Not;Not homeodomain protein;Noto;NOTO_HUMAN;notochord homolog (Xenopus laevis).
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  • NO.:SL19321R-Cy5.5
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Pig,Rabbit,)
    Applications:ICC IF
    concentration:1mg/ml
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Product Name Anti-NOTO/Cy5.5
Chinese Name Cy5.5标记的NOTO蛋白抗体
Alias floating head homolog; Homeobox protein notochord; Not; Not homeodomain protein; Noto; NOTO_HUMAN; notochord homolog (Xenopus laevis).  
Research Area Developmental biology  Neurobiology  transcriptional regulatory factor  Epigenetics  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Pig, Rabbit, )
Applications ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 27kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human NOTO
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
Transcription regulator acting downstream of both FOXA2 and T during notochord development. Required for node morphogenesis. Is essential for cilia formation in the posterior notochord (PNC) and for left-right patterning; acts upstream of FOXJ1 and RFX3 in this process and is required for the expression of various components important for axonemal assembly and function. Plays a role in regulating axial versus paraxial cell fate.

Subcellular Location:
Nucleus.

Similarity:
Contains 1 homeobox DNA-binding domain.

Database links:

Entrez Gene: 384452 Mouse

SwissProt: Q5TIS6 Mouse

Unigene: 347883 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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