Product Name	Anti-NAALADL2/Cy5.5
Chinese Name	Cy5.5标记的NAALADL2蛋白抗体
Alias	Glutamate carboxypeptidase II type non peptidase homologue; Inactive N acetylated alpha linked acidic dipeptidase like protein 2; Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2; N acetylated alpha linked acidic dipeptidase like 2; NAALADase L2; NAALADL 2; NAALADL2; NADL2_HUMAN.
Research Area	Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	38kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human NAALADL2
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: NAALADL2 is a 795 amino acid single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. Existing as two alternatively spliced isoforms, NAALADL2 is expressed at highest levels in placenta and kidney, and has also been observed in certain embryonic tissues. NAALADL2 may be catalytically inactive. The gene encoding NAALADL2 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3. Function: May be catalytically inactive. Subcellular Location: Membrane. Tissue Specificity: Expressed at higher level in kidney and placenta. In embryo, it is mainly confined to duodenal and stomach endoderm, mesonephros, metanephros and pancreas. Similarity: Belongs to the peptidase M28 family. M28B subfamily. Database links: Entrez Gene: 254827 Human Entrez Gene: 635702 Mouse Entrez Gene: 499583 Rat Omim: 608806 Human SwissProt: Q58DX5 Human Unigene: 565848 Human Unigene: 603646 Human Unigene: 660010 Human Unigene: 448351 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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