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Product Name Anti-LSM2/C6orf28/Cy5.5 Chinese Name Cy5.5标记的6号染色体开放阅读框28抗体 Alias C6orf28; Chromosome 6 open reading frame 28; G7b; LSM 2; Lsm2; LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae); Lsm2 protein; LSM2_HUMAN; OTTHUMP00000029159; Protein G7b; Small nuclear ribonuclear protein D homolog; snRNP; snRNP core Sm like protein Sm x5; snRNP core Sm-like protein Sm-x5; U6 snRNA associated Sm like protein LSm2; U6 snRNA-associated Sm-like protein LSm2; YBL026W. Research Area Cell biology Binding protein Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Cow, Rabbit, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 11kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human LSM2/C6orf28 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 19. [provided by RefSeq, Nov 2011]
Function:
Binds specifically to the 3'-terminal U-tract of U6 snRNA. May be involved in pre-mRNA splicing.
Subcellular Location:
Nucleus.
Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.
Similarity:
Belongs to the snRNP Sm proteins family.
Database links:Entrez Gene: 57819 Human
Entrez Gene: 27756 Mouse
Omim: 607282 Human
SwissProt: Q9Y333 Human
SwissProt: O35900 Mouse
Unigene: 103106 Human
Unigene: 165735 Mouse
Unigene: 216424 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Username | Quantity | bought time |
Na*** | 1 | 2024-09-19 |
Na*** | 2 | 2024-05-07 |
Vi*** | 1 | 2023-12-15 |
Ke*** | 2 | 2023-08-03 |
Da*** | 2 | 2023-07-11 |
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