TEL: +86 571 56623320 EMAIL: [email protected]
Product Name Anti-KCNK4/Cy5.5 Chinese Name Cy5.5标记的钾离子Channel protein4抗体 Alias K2p4.1; K2P4.1 potassium channel; KCNK 4; KCNK4_HUMAN; MGC144821; Potassium channel subfamily K member 4; Potassium inwardly rectifying channel subfamily K member 4; TRAAK; TRAAK1; TRAAKt; TWIK related arachidonic acid stimulated potassium channel protein; Two pore K(+) channel KT4.1; Two pore K+ channel KT4.1; Two pore potassium channel KT4.1. Research Area Cell biology Neurobiology Channel protein The cell membrane受体 Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 43kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human KCNK4 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
Potassium channels play a role in many cellular processes including maintenance of the action potential, muscle contraction, hormone secretion, osmotic regulation, and ion flow. This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The encoded protein homodimerizes and functions as an outwardly rectifying channel. It is expressed primarily in neural tissues and is stimulated by membrane stretch and polyunsaturated fatty acids. [provided by RefSeq, Jul 2008]
Function:
KCNK4 belongs to the two pore domain potassium channel family and is an outward rectifying potassium channel. This channel produces rapidly activating and non-inactivating outward rectifier K(+) currents. It is activated by arachidonic acid and other naturally occurring unsaturated free fatty acids.
Subunit:
Homodimer; disulfide-linked.
Subcellular Location:
Membrane; Multi-pass membrane protein.
Similarity:
Belongs to the two pore domain potassium channel (TC 1.A.1.8) family.
Database links:Entrez Gene: 50801 Human
Entrez Gene: 16528 Mouse
Omim: 605720 Human
SwissProt: Q9NYG8 Human
SwissProt: O88454 Mouse
Unigene: 647233 Human
Unigene: 12894 Mouse
Unigene: 46453 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Scan Wechat Qrcode
Scan Whatsapp Qrcode