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Product Name Anti-STARD8/AF594 Chinese Name AF594标记的GTP酶激活因子STARD8抗体 Alias Deleted in liver cancer 3; DLC3; StAR related lipid transfer protein 8; START domain containing protein 8; START GAP3; STAR8_HUMAN. Research Area Tumour Cell biology Signal transduction transcriptional regulatory factor G protein-coupled receptor Cytoskeleton Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, ) Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 113kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human STARD8 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
This gene encodes a member of a subfamily of Rho GTPase activating proteins that contain a steroidogenic acute regulatory protein related lipid transfer domain. The encoded protein localizes to focal adhesions and may be involved in regulating cell morphology. This protein may also function as a tumor suppressor.
Function:
Accelerates GTPase activity of RHOA and CDC42, but not RAC1. Stimulates the hydrolysis of phosphatidylinositol 4,5-bisphosphate by PLCD1
Subunit:
Binds both the SH2 and PTB domains of TNS1.
Subcellular Location:
Binds both the SH2 and PTB domains of TNS1.
Tissue Specificity:
Widely expressed with highest levels in kidney, lung and placenta.
Similarity:
Contains 1 Rho-GAP domain.
Contains 1 START domain.
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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