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Product Name Anti-AIFM3/AF594 Chinese Name AF594标记的凋亡诱导因子3抗体 Alias AIFL; Aifm3; AIFM3_HUMAN; Apoptosis inducing factor 3; Apoptosis inducing factor like; Apoptosis inducing factor like protein; Apoptosis inducing factor, mitochondrion associated; Apoptosis-inducing factor 3; Apoptosis-inducing factor-like protein; FLJ30473; FLJ45137. Research Area Cell biology Apoptosis Mitochondrion Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Cow, ) Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 67kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human AIFM3 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.
Function:
Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential.
Subcellular Location:
Mitochondrion. Note=Does not translocate to the nucleus upon induction of apoptosis.
Tissue Specificity:
Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).
Similarity:
Belongs to the FAD-dependent oxidoreductase family.
Contains 1 Rieske domain.
Database links:Entrez Gene: 150209 Human
Entrez Gene: 72168 Mouse
SwissProt: Q96NN9 Human
SwissProt: Q3TY86 Mouse
Unigene: 723246 Human
Unigene: 40038 Mouse
Unigene: 138718 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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