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Product Name Anti-CXXC5/AF594 Chinese Name AF594标记的二硫键氧化还原酶Zinc finger protein5抗体 Alias RINF; WID; CF5; CXXC finger protein 5; CXXC-type zinc finger protein 5; CXXC5; (Cys-Xaa-Xaa-Cys)5; CXXC5_HUMAN; HSPC195; Putative MAPK-activating protein PM08; Putative NF-kappa-B-activating protein 102; retinoid-inducible nuclear factor; WT1-induced Inhibitor of Dishevelled. Research Area Tumour Cell biology Signal transduction Stem cells Cyclin transcriptional regulatory factor Kinases and Phosphatases Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 24-34kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human CXXC5 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
May indirectly participate in activation of the NF-kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells.
Function:
May indirectly participate in activation of the NF-kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells (By similarity). Required for DNA damage-induced ATM phosphorylation, p53 activation and cell cycle arrest. Involved in myelopoiesis.
Subunit:
Interacts with DVL1 (By similarity).
Subcellular Location:
Nucleus. Cytoplasm (By similarity). Note=Colocalizes with DVL1 in large bodies localized just outside the nuclear membrane (By similarity).
Similarity:
Contains 1 CXXC-type zinc finger.
Database links:
UniProtKB/Swiss-Prot: Q7LFL8.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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