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Rabbit Anti-FAM101A/AF594 Conjugated antibody
Rabbit Anti-FAM101A/AF594 Conjugated antibody
cfm; 3110032G18Rik; cfm2; F101A_HUMAN; FAM101A; Family with sequence similarity 101, member A; FLJ44614; Hypothetical protein LOC73121; Protein FAM101A.
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Details

Product Name Anti-FAM101A/AF594
Chinese Name AF594标记的FAM101A蛋白抗体
Alias cfm; 3110032G18Rik; cfm2; F101A_HUMAN; FAM101A; Family with sequence similarity 101, member A; FLJ44614; Hypothetical protein LOC73121; Protein FAM101A.  
Research Area Cell biology  immunology  Developmental biology  
Immunogen Species Rabbit
Clonality Polyclonal
React Species
Applications ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 24kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from humna FAM101A
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Trisomy 12p leads to facial development defects, seizure disorders and a host of other symptoms varying in severity depending on the extent of mosaicism and is most severe in cases of complete trisomy. The FAM101A gene product has been provisionally designated FAM101A pending further characterization.

Similarity:
Belongs to the FAM101 family.

Database links:
UniProtKB/Swiss-Prot: Q6ZTI6.3

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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