Product Name	Anti-BRLF1/AF594
Chinese Name	AF594标记的EBV立即早期基因BRLF1抗体
Alias	Human herpesvirus 4 type 2
Research Area	Tumour  Cell biology  immunology  Bacteria and viruses
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,
Applications	IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	67kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human HHV4tp2 BRLF1
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: No data available. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. Epstein-Barr病毒(EB V)是疱疹病毒科γ亚科成员,是一种在人群中分布广泛的感染因子,在全世界90%以上人感染此病毒。E BV可引起人类的传染性单核细胞增多症,还与Burkitt’s淋巴瘤及鼻咽癌的发生密切相关。EB V的基因组长约172kb,基因组的末端有多个长约0.5kb的末端重复序列,可以使病毒基因组环化成环状游离体(episom e),并以此形式持续存在于受感染细胞的The nucleus内。EB V有潜伏周期和裂解周期两种状态。E BV进入细胞后,通常很快进入潜伏期,病毒基因组持续存在于细胞内。但病毒在受感染细胞的少数细胞中可以进入增殖期,并产生病毒颗粒。佛波酯、钙离子载体、丁酸盐、抗膜免疫球蛋白处理潜伏有EB V的Blymphocyte,都可以诱导E BV由潜伏状态转换到裂解状态。BZLF1(Bam H I片段Z左向第一读码框)和BRLF1(Bam H I片段R左向第一读码框)两个基因在病毒的潜伏周期转变为裂解周期的过程中起重要作用。

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