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Rabbit Anti-IGSF9/AF594 Conjugated antibody
Rabbit Anti-IGSF9/AF594 Conjugated antibody
IGSF9A; Dasm1; Dendrite arborization and synapse maturation protein 1; IGSF9 immunoglobulin superfamily, member 9; Immunoglobulin superfamily member 9A; immunoglobulin superfamily, member 9; Ncaml; Nrt1; Protein turtle homolog A; TUTLA_HUMAN.
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  • NO.:SL9199R-AF594
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,Mouse,Rat,Chicken,Dog,Pig,Cow,Rabbit,)
    Applications:IF
    concentration:1mg/ml
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Product Name Anti-IGSF9/AF594
Chinese Name AF594标记的免疫球蛋白超家族成员9抗体
Alias IGSF9A; Dasm1; Dendrite arborization and synapse maturation protein 1; IGSF9 immunoglobulin superfamily, member 9; Immunoglobulin superfamily member 9A; immunoglobulin superfamily, member 9; Ncaml; Nrt1; Protein turtle homolog A; TUTLA_HUMAN.  
Research Area Cell biology  Neurobiology  Cell Surface Molecule  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, )
Applications IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 124kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human IGSF9
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
Ig (immunoglobulin) superfamily members exhibit functional characteristics including immune responses, growth factor signaling and cell adhesion. IGSF9 (immunoglobulin superfamily, member 9), also known as Nrt1 or IGSF9A, is a 1,179 amino acid single-pass type I membrane protein expressed in a wide variety of fetal tissues at eight and fourteen weeks of gestation. Belonging to the immunoglobulin superfamily and the Turtle family, IGSF9 is thought to play a role in dendrite outgrowth and synapse maturation. IGSF9 contains two fibronectin type-III domains and five Ig-like (immunoglobulin-like) domains. IGSF9 interacts with MAGI-2 and Shank 1, both of which contain SH3 (Src-homology 3) domains. Protein-protein interactions are central events in cellular signal transduction and are often mediated by SH3 domains. IGSF9 is encoded by a gene located on human chromosome 1q23.2 and mouse chromosome 1 H3.

Function:
Functions in dendrite outgrowth and synapse maturation (By similarity).

Subunit:
Interacts with MAGI2 and SHANK1.

Subcellular Location:
Cell membrane; Single-pass type I membrane protein.

Similarity:
Belongs to the immunoglobulin superfamily. Turtle family.
Contains 2 fibronectin type-III domains.
Contains 5 Ig-like (immunoglobulin-like) domains.

Database links:

Entrez Gene: 57549 Human

Entrez Gene: 93842 Mouse

Entrez Gene: 304982 Rat

Omim: 609738 Human

SwissProt: Q9P2J2 Human

SwissProt: Q05BQ1 Mouse

SwissProt: P0C5H6 Rat

Unigene: 591472 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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