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Product Name Anti-IGSF9/AF594 Chinese Name AF594标记的免疫球蛋白超家族成员9抗体 Alias IGSF9A; Dasm1; Dendrite arborization and synapse maturation protein 1; IGSF9 immunoglobulin superfamily, member 9; Immunoglobulin superfamily member 9A; immunoglobulin superfamily, member 9; Ncaml; Nrt1; Protein turtle homolog A; TUTLA_HUMAN. Research Area Cell biology Neurobiology Cell Surface Molecule Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, ) Applications IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 124kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human IGSF9 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
Ig (immunoglobulin) superfamily members exhibit functional characteristics including immune responses, growth factor signaling and cell adhesion. IGSF9 (immunoglobulin superfamily, member 9), also known as Nrt1 or IGSF9A, is a 1,179 amino acid single-pass type I membrane protein expressed in a wide variety of fetal tissues at eight and fourteen weeks of gestation. Belonging to the immunoglobulin superfamily and the Turtle family, IGSF9 is thought to play a role in dendrite outgrowth and synapse maturation. IGSF9 contains two fibronectin type-III domains and five Ig-like (immunoglobulin-like) domains. IGSF9 interacts with MAGI-2 and Shank 1, both of which contain SH3 (Src-homology 3) domains. Protein-protein interactions are central events in cellular signal transduction and are often mediated by SH3 domains. IGSF9 is encoded by a gene located on human chromosome 1q23.2 and mouse chromosome 1 H3.
Function:
Functions in dendrite outgrowth and synapse maturation (By similarity).
Subunit:
Interacts with MAGI2 and SHANK1.
Subcellular Location:
Cell membrane; Single-pass type I membrane protein.
Similarity:
Belongs to the immunoglobulin superfamily. Turtle family.
Contains 2 fibronectin type-III domains.
Contains 5 Ig-like (immunoglobulin-like) domains.
Database links:
Entrez Gene: 57549 Human
Entrez Gene: 93842 Mouse
Omim: 609738 Human
SwissProt: Q9P2J2 Human
SwissProt: Q05BQ1 Mouse
Unigene: 591472 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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