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Product Name Anti-DNAH9/AF594 Chinese Name AF594标记的轴丝动力蛋白重链9抗体 Alias Dynein heavy chain; Axonemal beta dynein heavy chain 9; Ciliary dynein heavy chain 9; Ciliary dynein heavy chain; DNAH 9; DNAH17L; DNAH9; DNAH9 variant protein; Dnahc 9; Dnahc9; DNAL 1; DNAL1; DNEL 1; DNEL1; DYH 9; DYH9; Dynein axonemal heavy chain 9; Dynein axonemal heavy polypeptide 17 like; Dynein axonemal heavy polypeptide 9; dynein heavy chain 9, axonemal; HL 20; HL20; KIAA0357; DYH9_HUMAN. Research Area Neurobiology Signal transduction Cell adhesion molecule Cytoskeleton Extracellular matrix Immunogen Species Rabbit Clonality Polyclonal React Species Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 512kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human DNAH9 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
This gene encodes the heavy chain subunit of axonemal dynein, a large multi-subunit molecular motor. Axonemal dynein attaches to microtubules and hydrolyzes ATP to mediate the movement of cilia and flagella. The gene expresses at least two transcript variants; additional variants have been described, but their full length nature has not been determined. [provided by RefSeq, Jul 2008].
Function:
Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP.
Subunit:
Consists of at least two heavy chains and a number of intermediate and light chains.
Subcellular Location:
Cytoplasmic
Similarity:
Belongs to the dynein heavy chain family.
Database links:Entrez Gene: 1770 Human
Omim: 603330 Human
SwissProt: Q9NYC9 Human
Unigene: 567259 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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