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Product Name Anti-Calcyphosine 2/AF594 Chinese Name AF594标记的钙磷蛋白2抗体 Alias Calcyphosin 2; Calcyphosin-2; Calcyphosine-2; Calcyphosine2; Calcyphosphine 2; CAPS 2; CAPS2; CAYP2_HUMAN; D630005B03Rik; FLJ34520; OTTHUMP00000202412; OTTMUSP00000027695; UG0636c06. Research Area Cell biology Neurobiology Signal transduction The cell membrane受体 Binding protein Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Pig, Cow, Sheep, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 64kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human Calcyphosine 2/CAPS2 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
CAPS2 is a 557 amino acid calcium-binding protein that is abundantly expressed, with highest expression found in placenta, testis, colon, lung and brain. CAPS2 contains three EF-hand domains and exists as three alternatively spliced isoforms. Suggested to play a role in large dense-core vesicle (LDCV) exocytosis, CAPS2 is encoded by a gene that maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
Subcellular Location:
Cell membrane
Tissue Specificity:
Abundantly expressed in many tissues. Expressed in brain, colon, heart, kidney, liver, lung, liver, pancreas, placenta, skeletal muscle, testis and thymus. Highest expression in colon, testis, lung, placenta and brain.
Similarity:
Contains 3 EF-hand domains.
Database links:Entrez Gene: 93664 Human
Entrez Gene: 320405 Mouse
Omim: 609978 Human
SwissProt: Q86UW7 Human
SwissProt: Q8BYR5 Mouse
Unigene: 126730 Human
Unigene: 379572 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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