Product Name	Anti-G Protein alpha x+z/AF594
Chinese Name	AF594标记的G蛋白受体α x+z抗体
Alias	G(x) alpha chain; GNAZ; GNAZ_HUMAN; Guanine nucleotide binding protein (G protein) alpha z polypeptide; Guanine nucleotide binding protein G(z) alpha subunit G(x) alpha chain; Guanine nucleotide binding protein G(z) subunit alpha; Guanine nucleotide-binding protein G(z) subunit alpha; Gz alpha; Gz-alpha; Human Gx alpha gene; Transducin alpha.
Research Area	Cell biology  Signal transduction  G protein-coupled receptor  G protein signal
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	41kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human G protein alpha inhibitor 2
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Function: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. May play a role in cell division. Subunit: G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site. Subcellular Location: Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Cell membrane. Localizes in the centrosomes of interphase and mitotic cells. Detected at the cleavage furrow and/or the midbody. Similarity: Belongs to the G-alpha family. G(i/o/t/z) subfamily. Database links: UniProtKB/Swiss-Prot: P19086.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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