Product Name	Anti-Choline kinase alpha/AF594
Chinese Name	AF594标记的乙醇胺激酶α抗体
Alias	CHETK alpha; CHETK-alpha; CHK; CHKA; CK; CKI; EK; Ethanolamine kinase; CHKA_HUMAN.
Research Area	Tumour  Cell biology  Signal transduction  The new supersedes the old
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	52kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Choline kinase alpha
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. The protein encoded by this gene is the initial enzyme in the sequence and may play a regulatory role. The encoded protein also catalyzes the phosphorylation of ethanolamine. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Function: The dominant pathway for biosynthesis of phosphatidylcholine occurs through the CDP-choline pathway. Choline kinase alpha (CHK) is the first enzyme in the pathway and may thereby play an upstream regulatory role in lipid transport and metabolism. CHK additionally catalyzes phosphorylation of ethanolamine. Subunit: Heterodimer with CHKB (By similarity). Homodimer. Subcellular Location: Cytoplasmic Similarity: Belongs to the choline/ethanolamine kinase family. Database links: Entrez Gene: 1119 Human Entrez Gene: 12660 Mouse Entrez Gene: 29194 Rat Omim: 118491 Human SwissProt: P35790 Human SwissProt: O54804 Mouse SwissProt: Q01134 Rat Unigene: 77221 Human Unigene: 225505 Mouse Unigene: 10985 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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