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Rabbit Anti-HLA Class 1 ABC /HLA ABC/AF594 Conjugated antibody
Rabbit Anti-HLA Class 1 ABC /HLA ABC/AF594 Conjugated antibody
1A01_HUMAN; HLA A; HLA B; HLA C; HLAabc; HLA class 1 A; HLA class 1 B; HLA class 1 C; Major histocompatibility complex, class I, A + B + C; MHC class I HLA A; MHC class I HLA B; MHC class I HLA C; MHC HLA ABC.
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  • NO.:SL10634R-AF594
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Human,
    Applications:ICC IF
    concentration:1mg/ml
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Product Name Anti-HLA Class 1 ABC /HLA ABC/AF594
Chinese Name AF594标记的人类白细胞抗原A抗体
Alias 1A01_HUMAN; HLA A; HLA B; HLA C; HLAabc; HLA class 1 A; HLA class 1 B; HLA class 1 C; Major histocompatibility complex, class I, A + B + C; MHC class I HLA A; MHC class I HLA B; MHC class I HLA C; MHC HLA ABC.  
Research Area Tumour  Cell biology  immunology  The cell membrane受体  Cell Surface Molecule  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human, 
Applications ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 38kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human HLA Class 1 ABC
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail Function:
Involved in the presentation of foreign antigens to the immune system.

Subunit:
Dimer of alpha chain and a beta chain (beta-2-microglobulin). Interacts with human herpesvirus 8 MIR1 protein (By similarity).

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Post-translational modifications:
Sulfated.
Polyubiquitinated in a post ER compartment through interaction with human herpesvirus 8 MIR1 protein. This targets the protein for rapid degradation via the ubiquitin system (By similarity).

Similarity:
Belongs to the MHC class I family.
Contains 1 Ig-like C1-type (immunoglobulin-like) domain.

Database links:

Entrez Gene: 3105 Human

Omim: 142800 Human

SwissProt: P04439 Human

Unigene: 181244 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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