Product Name	Anti-TMEM157/AF594
Chinese Name	AF594标记的TMEM157蛋白抗体
Alias	F174A_HUMAN; FAM174A; HCV NS5A-transactivated protein 6; Hepatitis C virus NS5A-transactivated protein 6; Membrane protein FAM174A; NS5ATP6; RGD1309973; TMEM157; Transmembrane protein 157; UNQ1912/PRO4371.
Research Area	Cell biology  immunology  Bacteria and viruses
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	17kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human TMEM157
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: TMEM157 is 190 amino acid protein encoded by a gene mapping to human chromosome 5. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. Subcellular Location: Membrane. Similarity: Belongs to the FAM174 family. Database links: Entrez Gene: 345757 Human SwissProt: Q8TBP5 Human Unigene: 729005 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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