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Product Name Anti-SNX32/AF594 Chinese Name AF594标记的选择连接蛋白32抗体 Alias DKFZp761P1320; FLJ30934; MGC42112; MGC57276; SNX32; SNX32_HUMAN; SNX6B; Sortin nexin 32; Sortin nexin 6B; Sorting nexin-32; Sorting nexin-6B. Research Area Cell biology immunology Signal transduction Transporter Immunogen Species Rabbit Clonality Polyclonal React Species Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 46kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SNX32 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
SNX32 is a 403 amino acid protein that contains one PX (phox homology) domain and belongs to the sorting nexin family. Existing as two alternatively spliced isoforms, SNX32 may be involved in several stages of intracellular trafficking. The gene that encodes SNX32 consists of approximately 23,256 bases and maps to human chromosome 11q13.1. Housing over 1,400 genes and comprising nearly 4% of the human genome, chromosome 11 is considered a gene and disease association-dense chromosome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that map to chromosome 11. In addition, the blood disorders Sickle cell anemia and thalassemia are caused by mutations in the HBB gene, which is located on chromosome 11.
Function:
May be involved in several stages of intracellular trafficking.
Similarity:
Belongs to the sorting nexin family.
Contains 1 PX (phox homology) domain.
Database links:Entrez Gene: 254122 Human
SwissProt: Q86XE0 Human
Unigene: 591950 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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