Product Name	Anti-NOSIP/AF594
Chinese Name	AF594标记的一氧化氮合成酶相互作用蛋白抗体
Alias	CGI 25; CGI-25; NOSIP_HUMAN; CGI25; CGI25 protein; eNOS interacting protein; Nitric oxide synthase interacting protein.
Research Area	Neurobiology  Signal transduction  Transporter
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	33kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human NOSIP
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: The protein encoded by this gene may modulate the activity and localization of nitric oxide synthase (endothelial and neuronal) and thus nitric oxide production. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2012] Function: NOSIP is a novel type of modulator that promotes translocation of eNOS from the plasma membrane to intracellular sites, thereby uncoupling eNOS from plasma membrane caveolae and inhibiting NO synthesis. Subunit: Interacts with NOS1 and NOS3. Subcellular Location: Cytoplasm. Nucleus. Note: Translocates from nucleus to cytoplasm in the G2 phase of the cell cycle. Tissue Specificity: Expressed in heart, brain and lung. Present in endothelial cells (at protein level). Similarity: Belongs to the NOSIP family. Database links: Entrez Gene: 51070 Human Entrez Gene: 511234 Cow Entrez Gene: 66394 Mouse Entrez Gene: 292894 Rat SwissProt: Q3SWY5 Cow SwissProt: Q9Y314 Human SwissProt: Q9D6T0 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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