Product Name	Anti-KBTBD7/AF594
Chinese Name	AF594标记的KBTBD7蛋白抗体
Alias	1110008P08Rik; AU045792; DKFZP434E2318; Gm295; KBTB7_HUMAN; KBTBD 7; KBTBD7; Kelch repeat and BTB (POZ) domain containing 7; Kelch repeat and BTB domain containing protein 7; Kelch repeat and BTB domain-containing protein 7; OTTHUMP00000018313.
Research Area	Cell biology  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	70kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human KBTBD7
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. The Kelch repeat and BTB domain-containing protein 7 (KBTBD7) contains 1 BTB (POZ) domain and 5 Kelch repeats suggesting a role in transcription regulation. The gene encoding KBTBD7 maps to chromosome 13, which contains 400 genes including key tumor suppressor genes such as the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. Similarity: Contains 1 BTB (POZ) domain. Contains 5 Kelch repeats. Database links: Entrez Gene: 84078 Human Entrez Gene: 211255 Mouse Entrez Gene: 306073 Rat GenBank: NM_032138 Human SwissProt: Q8WVZ9 Human Unigene: 63841 Human Unigene: 284526 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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