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Product Name Anti-ITPKB/AF594 Chinese Name AF594标记的三磷酸肌醇3激酶B抗体 Alias 1D myo inositol trisphosphate 3 kinase B; 4; 5-trisphosphate 3-kinase B; Inositol 1 4 5 trisphosphate 3 kinase B; Inositol 1; Inositol trisphosphate 3 kinase B; Inositol-trisphosphate 3-kinase B; InsP 3-kinase B; IP3 3 kinase; IP3 3 kinase B; IP3 3-kinase B; IP3K; IP3K B; IP3KB; IP3KB_HUMAN; Itpkb. Research Area Cell biology Signal transduction Kinases and Phosphatases Immunogen Species Rabbit Clonality Polyclonal React Species Rat, (predicted: Human, Mouse, Chicken, Dog, Cow, Horse, Sheep, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 102kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human ITPKB Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
The protein encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. [provided by RefSeq, Jul 2008]
Subunit:
Interacts with DMTN.
Similarity:
Belongs to the inositol phosphokinase (IPK) family.
Database links:Entrez Gene: 3707 Human
Entrez Gene: 320404 Mouse
Omim: 147522 Human
SwissProt: P27987 Human
Unigene: 659396 Human
Unigene: 726323 Human
Unigene: 132535 Mouse
Unigene: 22498 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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