Product Name	Anti-OTOP1/AF594
Chinese Name	AF594标记的OTOP1蛋白抗体
Alias	A530025J20Rik; otop1; OTOP1_HUMAN; Otopetrin-1; Otp1; Tilted; tlt.
Research Area	Cell biology  Signal transduction  G protein signal
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, )
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	67kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human OTOP1
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: Required for normal formation of otoconia in the inner ear. Inhibits P2Y purinoceptors. Modulates calcium homeostasis and influx of calcium in response to extracellular ATP. Subcellular Location: Membrane. Secreted > extracellular space. Detected in the gelatinous membrane overlying the inner ear macular epithelium. Similarity: Belongs to the otopetrin family. Database links: Entrez Gene: 133060 Human Entrez Gene: 21906 Mouse Omim: 607806 Human SwissProt: Q7RTM1 Human SwissProt: Q80VM9 Mouse Unigene: 534544 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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