Product Name	Anti-MOCS2/AF594
Chinese Name	AF594标记的钼辅因子合成蛋白2抗体
Alias	MCBPE; MOCO1; MOCO1 B; MOCO1B; MOCS 2; MOCS2; MOCS2A; MOCS2B; Molybdenum cofactor biosynthesis protein E; Molybdenum cofactor synthesis 2; Molybdenum cofactor synthesis protein 2 large subunit; molybdenum cofactor synthesis protein 2 small subunit; molybdenum cofactor synthesis protein 2A; Molybdenum cofactor synthesis protein 2B; Molybdopterin synthase; Molybdopterin synthase large subunit; molybdopterin-synthase small subunit; MPT synthase; MPTS; OTTHUMP00000122459; sulfur carrier protein MOCS2A.
Research Area	Cell biology  Signal transduction  The new supersedes the old
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	21kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human MOCS2
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: Eukaryotic molybdoenzymes use a unique molybdenum cofactor (MoCo) consisting of a pterin, termed molybdopterin, and the catalytically active metal molybdenum. MoCo is synthesized from precursor Z by the heterodimeric enzyme molybdopterin synthase. The large and small subunits of molybdopterin synthase are both encoded from this gene by overlapping open reading frames. The proteins were initially thought to be encoded from a bicistronic transcript. They are now thought to be encoded from monocistronic transcripts. Alternatively spliced transcripts have been found for this locus that encode the large and small subunits. [provided by RefSeq, Jul 2008] Function: The large (MOCS2B) and small (MOCS2A) subunits of molybdopterin synthase are both encoded from the MOCS2 gene by overlapping open reading frames. MOCS2B is the catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. It acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group. Subunit: Heterotetramer; composed of 2 small (MOCS2A) and 2 large (MOCS2B) subunits. Subcellular Location: Cytoplasmic Tissue Specificity: Highest levels are found in heart and skeletal muscle. Lower levels are present in brain, kidney and pancreas.Very low levels are found in lung and peripheral blood leukocytes. DISEASE: Molybdenum cofactor deficiency, complementation group B(MOCODB) Similarity: Belongs to the MoaE family. MOCS2B subfamily. Database links: Entrez Gene: 4338 Human Omim: 603708 Human SwissProt: O96007 Human Unigene: 163645 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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