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Product Name Anti-LUC7L2/AF594 Chinese Name AF594标记的LUC7L2蛋白抗体 Alias CGI 59; CGI 74; FLJ10657; hLuc7B2; LC7L2_HUMAN; LUC7 like 2 (S. cerevisiae); LUC7B2; LUC7L2; Putative RNA binding protein Luc7 like 2; Putative RNA-binding protein Luc7-like 2. Research Area Cell biology immunology Binding protein Epigenetics Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Sheep, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 47kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human LUC7L2 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
This gene encodes a protein that contains a C2H2-type zinc finger, coiled-coil region and arginine, serine-rich (RS) domain. A similar protein in mouse interacts with sodium channel modifier 1, and the encoded protein may be involved in the recognition of non-consensus splice donor sites in association with the U1 snRNP spliceosomal subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]
Function:
May bind to RNA via its Arg/Ser-rich domain.
Subcellular Location:
Nucleus speckle. Nucleus > nucleoplasm. Colocalizes with SCNM1 and SNRNP70 in nuclear speckles.
Similarity:
Belongs to the Luc7 family.
Database links:Entrez Gene: 51631 Human
Entrez Gene: 192196 Mouse
Omim: 613056 Human
SwissProt: Q9Y383 Human
SwissProt: Q7TNC4 Mouse
Unigene: 370475 Human
Unigene: 731488 Human
Unigene: 276133 Mouse
Unigene: 479854 Mouse
Unigene: 482221 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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