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Product Name Anti-MAGEA6/AF594 Chinese Name AF594标记的黑色素瘤相关抗原6抗体 Alias Cancer/testis antigen 1.6; Cancer/testis antigen family 1, member 6; CT1.6; MAGA6_HUMAN; MAGE 3b; MAGE 6 antigen; MAGE-6 antigen; MAGE3B; MAGE3B antigen; MAGE6; MAGEA6; Melanoma antigen family A 6; Melanoma associated antigen 6; Melanoma-associated antigen 6. Research Area Tumour Cell biology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Cynomolgus Monkey) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 35kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human MAGEA6 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Tissue Specificity:
Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes.
Similarity:
Contains 1 MAGE domain.
Database links:Entrez Gene: 4105 Human
Entrez Gene: 17142 Mouse
Omim: 300176 Human
SwissProt: P43360 Human
SwissProt: Q6NW44 Human
Unigene: 441113 Human
Unigene: 377098 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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