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Product Name Anti-GPR50/Melatonin Related Receptor/AF594 Chinese Name AF594标记的褪黑激素相关受体抗体 Alias G protein coupled receptor 50; G protein-coupled receptor 50; GPR 50; Gpr50; H9; Mel1c; Melatonin-related receptor; MGC125342; MTNRL; MTR1L_HUMAN. Research Area Neurobiology G protein-coupled receptor G protein signal Immunogen Species Rabbit Clonality Polyclonal React Species Human, (predicted: Mouse, Rat, Dog, Horse, Rabbit, Cat, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 67kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human GPR50/Melatonin Related Receptor Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
This gene product belongs to the G-protein coupled receptor 1 family. Even though this protein shares similarity with the melatonin receptors, it does not bind melatonin, however, it inhibits melatonin receptor 1A function through heterodimerization. Polymorphic variants of this gene have been associated with bipolar affective disorder in women. [provided by RefSeq, Jan 2010]
Subcellular Location:
Cell membrane.
Tissue Specificity:
Hypothalamus and pituitary.
Similarity:
Belongs to the G-protein coupled receptor 1 family.
Database links:
Entrez Gene: 9248 Human
Omim: 300207 Human
SwissProt: Q13585 Human
Unigene: 567390 Human
Unigene: 92385 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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