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Product Name Anti-NANP/AF594 Chinese Name AF594标记的N-乙酰神经氨酸磷酸酶 Alias 1600031M04Rik; C20orf147; dJ694B14.3; Haloacid dehalogenase like hydrolase domain containing 4; Haloacid dehalogenase like hydrolase domain containing protein 4; Haloacid dehalogenase-like hydrolase domain-containing protein 4; HDHD4; MGC103377; MGC105812; MGC26833; N acetylneuraminic acid phosphatase; N acylneuraminate 9 phosphatase; N-acylneuraminate-9-phosphatase; Nanp; NANP_HUMAN; Neu5Ac 9 Pase; Neu5Ac-9-Pase; OTTMUSP00000016814; RGD1306009; RP23-193L22.6. Research Area Tumour Cell biology Neurobiology Signal transduction The new supersedes the old Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 28kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human NANP Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
NANP is a 248 amino acid protein that belongs to the haloacid dehalogenase (HAD) family and is responsible for dephosphorylating Neu5Ac-9-phosphate to form N-acetylneuraminate. Characteristic of the HAD phosphatase family, the catalytic activity of NANP is dependent upon the presence of magnesium and is inhibited by vanadate and calcium.
Similarity:
Belongs to the HAD-like hydrolase superfamily. NANP family.
Database links:Entrez Gene: 140838 Human
Entrez Gene: 67311 Mouse
Omim: 610763 Human
SwissProt: Q8TBE9 Human
SwissProt: Q9CPT3 Mouse
Unigene: 143137 Human
Unigene: 606268 Human
Unigene: 480682 Mouse
Unigene: 210573 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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