Product Name	Anti-ABI3/AF594
Chinese Name	AF594标记的ABI基因家族2抗体
Alias	ABI gene family member 3; Nesh; New molecule including SH3; ABI3_HUMAN.
Research Area	Tumour  immunology
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, )
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	39kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human ABI3
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: ABI3 is thought to inhibit tumor metastasis. In vitro, ABI3 reduces cell motility. Function: May inhibit tumor metastasis. In vitro, reduces cell motility. Subunit: May interact with PAK1 and PAK2. Probably interacts with TARSH. Subcellular Location: Cytoplasm. Note=Colocalizes with PAK2 at leading edge of cells. Tissue Specificity: Expressed in heart, lung, liver, pancreas, kidney, placenta and at low levels in brain and skeletal muscle. Similarity: Belongs to the ABI family. Contains 1 SH3 domain. Database links: Entrez Gene: 538604 Cow Entrez Gene: 478544 Dog Entrez Gene: 100723639 Guinea pig Entrez Gene: 25890 Human Entrez Gene: 320712 Mouse Entrez Gene: 100154641 Pig Entrez Gene: 363767 Rat Entrez Gene: 100149890 Zebrafish Omim: 606279 Human SwissProt: Q7Z7G0 Human Unigene: 477015 Human Unigene: 209236 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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