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Product Name Anti-NUDCD2/AF594 Chinese Name AF594标记的NUDCD2蛋白抗体 Alias NudC domain containing 2; NudC domain-containing protein 2; NudC like protein 2; NUDC2_HUMAN; Nudcd2. Research Area Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 18kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human NUDCD2 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail Function:
May regulate the LIS1/dynein pathway by stabilizing LIS1 with Hsp90 chaperone.
Subunit:
Interacts with LIS1.
Subcellular Location:
Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:20133715}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:20133715}. Note=Associates with centrosomes in interphase and to spindle poles and kinetochores during mitosis.
Similarity:
Contains 1 CS domain. {ECO:0000255|PROSITE-ProRule:PRU00547}.
Database links:Entrez Gene: 134492 Human
Entrez Gene: 52653 Mouse
SwissProt: Q8WVJ2 Human
SwissProt: Q9CQ48 Mouse
Unigene: 140443 Human
Unigene: 276504 Mouse
Unigene: 3419 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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