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Product Name Anti-RASGEF1C/AF594 Chinese Name AF594标记的RASGEF1C蛋白抗体 Alias FLJ35841; OTTHUMP00000161522; RGF1C_HUMAN; Ras GEF domain containing family member 1C; RASGEF 1C; RasGEF domain containing family member 1C; RasGEF domain family member 1C. Research Area Cell biology Signal transduction G protein-coupled receptor G protein signal Immunogen Species Rabbit Clonality Polyclonal React Species Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 53kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human RASGEF1C Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
RasGEF1c is a guanine nucleotide exchange factor (GEF) for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. There are two isoforms.
Function:
Guanine nucleotide exchange factor (GEF).
Similarity:
Contains 1 N-terminal Ras-GEF domain.
Contains 1 Ras-GEF domain.
Database links:Entrez Gene: 255426 Human
Entrez Gene: 74563 Mouse
SwissProt: Q8N431 Human
SwissProt: Q9D300 Mouse
Unigene: 190559 Human
Unigene: 258798 Mouse
Unigene: 46134 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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