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Product Name Anti-SLC10A6/AF594 Chinese Name AF594标记的溶质载体家族蛋白10成员A6抗体 Alias MGC129575; MGC129576; Slc10a6; SOAT; SOAT_HUMAN; Sodium dependent organic anion transporter; Sodium-dependent organic anion transporter; Solute carrier family 10 member 6. Research Area Tumour Cell biology Signal transduction The cell membrane蛋白 Immunogen Species Rabbit Clonality Polyclonal React Species Human, Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 42kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human SLC10A6 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
SLC10A6 (Solute Carrier Family 10 Member 6) is a Protein Coding gene. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds. GO annotations related to this gene include bile acid:sodium symporter activity and sodium-dependent organic anion transmembrane transporter activity. An important paralog of this gene is SLC10A2.
Function:
Transports sulfoconjugated steroid hormones, as well as taurolithocholic acid-3-sulfate and sulfoconjugated pyrenes in a sodium-dependent manner.
Subcellular Location:
Membrane.
Tissue Specificity:
Highly expressed in testis, placenta and pancreas. Moderately expressed in heart, lung and mammary gland. Weakly expressed in brain, colon, kidney, liver, ovary, prostate, small intestine, spleen and thymus.
Post-translational modifications:
Glycosylated.
Similarity:
Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.
Database links:Entrez Gene: 345274 Human
GenBank: NM_197965 Human
SwissProt: Q3KNW5 Human
Unigene: 452996 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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