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Rabbit Anti-PEBP4/AF594 Conjugated antibody
Rabbit Anti-PEBP4/AF594 Conjugated antibody
1700051A02Rik; 1700081D17Rik; AI429082; CORK 1; CORK1; Cousin of RKIP 1 protein; GWTM1933; hPEBP4; MGC22776; PEBP 4; Phosphatidylethanolamine binding protein 4; PRO4408; Protein cousin of RKIP 1; UNQ1933/PRO4408.
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  • NO.:SL12610R-AF594
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:(predicted: Human,)
    Applications:ICC IF
    concentration:1mg/ml
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Product Name Anti-PEBP4/AF594
Chinese Name AF594标记的磷脂酰乙醇胺Binding protein4抗体
Alias 1700051A02Rik; 1700081D17Rik; AI429082; CORK 1; CORK1; Cousin of RKIP 1 protein; GWTM1933; hPEBP4; MGC22776; PEBP 4; Phosphatidylethanolamine binding protein 4; PRO4408; Protein cousin of RKIP 1; UNQ1933/PRO4408.  
Research Area Tumour  Cell biology  Apoptosis  Kinases and Phosphatases  Binding protein  
Immunogen Species Rabbit
Clonality Polyclonal
React Species (predicted: Human, )
Applications ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 26kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human PEBP4
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
The phosphatidylethanolamine (PE)-binding proteins, including PEBP4, are an evolutionarily conserved family of proteins with pivotal biologic functions, such as lipid binding and inhibition of serine proteases (Wang et al., 2004 [PubMed 15302887]).[supplied by OMIM, Dec 2008]

Function:
Seems to promote cellular resistance to TNF-induced apoptosis by inhibiting activation of the Raf-1/MEK/ERK pathway, JNK and phosphatidylethanolamine externalization

Subcellular Location:
Lysosome

Tissue Specificity:
Ubiquitously expressed. Highly expressed in tumor cells.

Similarity:
Belongs to the phosphatidylethanolamine-binding protein family.

Database links:

Entrez Gene: 157310 Human

Omim: 612473 Human

SwissProt: Q96S96 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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