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Rabbit Anti-SLC22A11/AF594 Conjugated antibody
Rabbit Anti-SLC22A11/AF594 Conjugated antibody
hOAT4; MGC34282; OAT4; Organic anion transporter 4; Solute carrier family 22 (organic anion/urate transporter) member 11; Solute carrier family 22 member 11.
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  • NO.:SL20723R-AF594
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Human,
    Applications:ICC IF
    concentration:1mg/ml
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Product Name Anti-SLC22A11/AF594
Chinese Name AF594标记的有机阴离子转运体4抗体
Alias hOAT4; MGC34282; OAT4; Organic anion transporter 4; Solute carrier family 22 (organic anion/urate transporter) member 11; Solute carrier family 22 member 11.   
Research Area Tumour  Signal transduction  Growth factors and hormones  Channel protein  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Human, 
Applications ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 60kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human SLC22A11
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and is found mainly in the kidney and in the placenta, where it may act to prevent potentially harmful organic anions from reaching the fetus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

Function:
Mediates saturable uptake of estrone sulfate, dehydroepiandrosterone sulfate and related compounds.

Subcellular Location:
Cell membrane, Multi-pass membrane protein.

Tissue Specificity:
Detected in placenta and kidney.

Post-translational modifications:
N-glycosylated. Contains several complex-type N-glycans.

Similarity:
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.

Database links:

Entrez Gene: 55867 Human

Omim: 607097 Human

SwissProt: Q9NSA0 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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