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Product Name Anti-MTCH1/AF555 Chinese Name AF555标记的细胞增殖诱导蛋白60(早老素相关蛋白) Alias Cell proliferation inducing protein 60; CGI-64; CGI64; Mitochondrial carrier homolog 1; Mitocondrial Carrier Homolog 1; MTCH 1; Mtch1; MTCH1_HUMAN; Presenilin Associated Protein; Presenilin-associated protein; PSAP. Research Area Cell biology Neurobiology Signal transduction Apoptosis Mitochondrion Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Rat, Pig, Guinea Pig, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 42kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human MTCH1 Lsotype IgG Purification affinity purified by Protein A Storage Buffer Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4. Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
This gene encodes a member of the mitochondrial carrier family. The encoded protein is localized to the mitochondrion inner membrane and induces apoptosis independent of the proapoptotic proteins Bax and Bak. Pseudogenes on chromosomes 6 and 11 have been identified for this gene. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Oct 2012]
Function:
Potential mitochondrial transporter. May play a role in apoptosis.
Subunit:
Interacts with PSEN1.
Subcellular Location:
Mitochondrion inner membrane; Multi-pass membrane protein (Potential).
Tissue Specificity:
Widely expressed with a predominant expression in brain.
Similarity:
Belongs to the mitochondrial carrier family.
Contains 2 Solcar repeats.
Database links:Entrez Gene: 23787 Human
Omim: 610449 Human
SwissProt: Q9NZJ7 Human
Unigene: 485262 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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