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Rabbit Anti-STK35/AF555 Conjugated antibody
Rabbit Anti-STK35/AF555 Conjugated antibody
CLIK-1; Clik1; CLP 36 interacting kinase; CLP-36-interacting kinase 1; EC 2.7.1.37; PDLIM1 interacting kinase; PDLIM1-interacting kinase 1; Serine threonine kinase 35 long form; Serine/threonine kinase 35; Serine/threonine protein kinase 35; Serine/threon
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  • NO.:SL12834R-AF555
    Clonality:Polyclonal
    Immunogen Species:Rabbit
    React Species:Rat,(predicted: Human,Mouse,Pig,)
    Applications:ICC IF
    concentration:1mg/ml
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Product Name Anti-STK35/AF555
Chinese Name AF555标记的丝氨酸/苏氨酸蛋白激酶35抗体
Alias CLIK-1; Clik1; CLP 36 interacting kinase; CLP-36-interacting kinase 1; EC 2.7.1.37; PDLIM1 interacting kinase; PDLIM1-interacting kinase 1; Serine threonine kinase 35 long form; Serine/threonine kinase 35; Serine/threonine protein kinase 35; Serine/threonine-protein kinase 35; Serine/threonine-protein kinase 35 L1; STK35; STK35_HUMAN; STK35L1.  
Research Area Cell biology  Signal transduction  Kinases and Phosphatases  Cytoskeleton  
Immunogen Species Rabbit
Clonality Polyclonal
React Species Rat,  (predicted: Human, Mouse, Pig, )
Applications ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
Molecular weight 58kDa
Form Lyophilized or Liquid
Concentration 1mg/ml
immunogen KLH conjugated synthetic peptide derived from human STK35
Lsotype IgG
Purification affinity purified by Protein A
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail background:
The protein encoded by this gene is a kinase that is predominantly found in the nucleus. However, it can interact with PDLIM1/CLP-36 in the cytoplasm and localize to actin stress fibers. The encoded protein may be a regulator of actin stress fibers in nonmuscle cells. [provided by RefSeq, Jul 2008]

Subcellular Location:
Nucleus. Nucleus > nucleolus. Cytoplasm. When associated with PDLIM1, it is mostly found in cytoplasm, localized to actin stress fibers (PubMed:11973348). However, PubMed:19756140 detected STK35 only in the nucleus, and the presence of PDLIM1 had no influence on its location.

Tissue Specificity:
Expressed in testis.

Post-translational modifications:
Autophosphorylated.

Similarity:
Belongs to the protein kinase superfamily.
Ser/Thr protein kinase family.
Contains 1 protein kinase domain.

Database links:

Entrez Gene: 140901 Human

Entrez Gene: 311419 Rat

GenBank: NP_543026 Human

Omim: 609370 Human

SwissProt: Q8TDR2 Human

Unigene: 100057 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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