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Product Name Anti-PODN/AF555 Chinese Name AF555标记的PODN蛋白抗体 Alias 9430070G18; LRRGT00160; MGC24995; PCAN; Podn; PODN_HUMAN; Podocan; Podocan proteoglycan; RP23 40G2.7; SLRR5A. Research Area Cell biology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species Mouse, (predicted: Human, Dog, Cow, Horse, Sheep, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 67kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human PODN Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail Function:
Negatively regulates cell proliferation and cell migration.
Subcellular Location:
Cytoplasm and Secreted > extracellular space > extracellular matrix.
Tissue Specificity:
Kidney, heart, liver, pancreas and vascular smooth muscle cells.
Post-translational modifications:
N-glycosylated.
Similarity:
Belongs to the small leucine-rich proteoglycan (SLRP) family.
SLRP class V subfamily.
Contains 20 LRR (leucine-rich) repeats.
Contains 1 LRRNT domain.
Database links:Entrez Gene: 127435 Human
Entrez Gene: 242608 Mouse
GenBank: BC030608 Human
Omim: 608661 Human
SwissProt: Q7Z5L7 Human
SwissProt: Q7TQ62 Mouse
Unigene: 586141 Human
Unigene: 733377 Human
Unigene: 74710 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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