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Product Name Anti-NRSN2/AF555 Chinese Name AF555标记的神经囊泡膜蛋白2抗体 Alias C20orf98; Neurensin 2; Neurensin-2; NRSN 2; NRSN2; NRSN2_HUMAN. Research Area Cell biology Neurobiology Signal transduction The cell membrane蛋白 Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Dog, Pig, Cow, Sheep, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 22kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human NRSN2 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
Neurensin-2 is a 204 amino acid multi-pass membrane protein belonging to the VMP family that may be involved in the transport and maintenance of vesicles. Expressed in brain, Neurensin-2 localizes to cell bodies of hippocampus, diagonal band, amygdaloid nucleus, and habenula nucleus, and is a potential tumor suppressor gene and candidate biomarker for long-term survival in patients with hepatocellular carcinoma (HCC). The gene encoding Neurensin-2 maps to human chromosome 20, which comprises approximately 2% of the human genome, contains nearly 63 million bases and encodes over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception.
Function:
May play a role in maintenance and/or transport of vesicles.
Subcellular Location:
Membrane.
Similarity:
Belongs to the VMP family.
Database links:Entrez Gene: 80023 Human
Omim: 610666 Human
SwissProt: Q9GZP1 Human
Unigene: 416024 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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