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Product Name Anti-MYO5C/AF555 Chinese Name AF555标记的肌球蛋白5C抗体 Alias Myosin Vc; MYO5C; MYO5C_HUMAN; Unconventional myosin-Vc. Research Area Cell biology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 203,48kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human MYO5C Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
Myosin Vc is a 1,742 amino acid protein that is chiefly expressed in non-neuronal tissues. Abundantly expressed in epithelial and glandular tissues including pancreas, prostate, mammary, stomach, colon and lung, Myosin Vc may be involved in transferrin trafficking and is likely to power actin-based membrane trafficking in many physiologically crucial tissues. Myosin Vc is also thought to participate in apical exocytosis of secretory vesicles. Containing one dilute domain, six IQ domains and a myosin head-like domain, Myosin Vc associates with Rab 8.
Function:
May be involved in transferrin trafficking. Likely to power actin-based membrane trafficking in many physiologically crucial tissues.
Tissue Specificity:
Expressed chiefly in non-neuronal tissues. Particularly abundant in epithelial and glandular tissues including pancreas, prostate, mammary, stomach, colon and lung.
Similarity:
Contains 1 dilute domain.
Contains 5 IQ domains.
Contains 1 myosin head-like domain.
Database links:Entrez Gene: 55930 Human
SwissProt: Q9NQX4 Human
Unigene: 487036 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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