Product Name	Anti-MANSC1/AF555
Chinese Name	AF555标记的MANSC1蛋白抗体
Alias	9130403P13Rik; FLJ10298; LOH12CR3; Loss of heterozygosity 12 chromosomal region 3 protein; MANS1_HUMAN; MANSC domain containing 1; MANSC domain-containing protein 1; MANSC1.
Research Area	Cell biology  immunology  The cell membrane蛋白
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, Dog, Cow, Horse, Sheep, )
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	44kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human MANSC1
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: MANSC1 is a 414 amino acid single-pass membrane protein. Expressed throughout the body, MANSC1 contains one MANSC domain and is encoded by a gene that is located on chromosome 12. Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5% of the human genome. A number of skeletal deformities are linked to chromosome 12, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction. Subcellular Location: Membrane. Tissue Specificity: Widely expressed. Similarity: Contains 1 MANSC domain. Database links: Entrez Gene: 54682 Human Entrez Gene: 67729 Mouse Entrez Gene: 690606 Rat SwissProt: Q9H8J5 Human SwissProt: Q9CR33 Mouse Unigene: 591145 Human Unigene: 57648 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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