Product Name	Anti-ZNF366/AF555
Chinese Name	AF555标记的Zinc finger protein366抗体
Alias	DC-SCRIPT; DCSCRIPT; Dendritic cell specific transcript; FLJ39796; MGC99415; Zfp366; Zfp366 zinc finger protein 366; Zinc finger protein 366; ZN366_HUMAN; ZNF366.
Research Area	transcriptional regulatory factor  Zinc finger protein  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Sheep, )
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	85kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human ZNF366
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: ZNF366 is a 744 amino acid nuclear protein that contains eleven C2H2-type zinc fingers and is thought to function in transcriptional regulation. The gene encoding ZNF366 maps to human chromosome 5, which contains 181 million base pairs and comprises nearly 6% of the human genome. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. Function: Has transcriptional repression activity. Acts as corepressor of ESR1; the function seems to involve CTBP1 and histone deacetylases. Subunit: Interacts with ESR1, NRIP1 and CTBP1. Subcellular Location: Nucleus. Similarity: Contains 11 C2H2-type zinc fingers. Database links: Entrez Gene: 167465 Human Entrez Gene: 238803 Mouse Entrez Gene: 100360041 Rat Omim: 610159 Human SwissProt: Q8N895 Human Unigene: 370303 Human Unigene: 343207 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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