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Product Name Anti-RNF192/AF555 Chinese Name AF555标记的Ring finger protein192抗体 Alias FLJ45273; LON peptidase N terminal domain and ring finger 2; LON peptidase N terminal domain and RING finger protein 2; LONRF 2; MGC126711; MGC126713; Neuroblastoma apoptosis related protease; RING finger protein 192; RNF 192; RNF192. Research Area Cell biology immunology Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 84kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human RNF192 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. LONRF2 is a 754 amino acid protein containing one LON domain, one RING-type zinc finger and six TPR repeats. Two isoforms of LONRF2 are produced by alternative splicing events. The gene encoding LONRF2 maps to human chromosome 2q11.2 and mouse chromosome 1 B.
Function:
LONRF2 contains one Lon domain, one RING type zinc finger and six TPR repeats. The function of LONRF2 is unknown. There are two named isoforms.
Similarity:
Contains 1 Lon domain. Contains 1 RING-type zinc finger. Contains 6 TPR repeats.
Database links:
Entrez Gene: 164832 Human
Entrez Gene: 381338 Mouse
SwissProt: Q1L5Z9 Human
SwissProt: B2RT44 Mouse
Unigene: 21380 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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