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Product Name Anti-HMX1/AF555 Chinese Name AF555标记的HMX1蛋白抗体 Alias H6 homeodomain protein; Homoeobox (H6 family) 1. HMX1_HUMAN Research Area Cell biology Developmental biology Signal transduction Immunogen Species Rabbit Clonality Polyclonal React Species (predicted: Human, Mouse, Rat, Dog, Pig, Cow, ) Applications ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.Molecular weight 36kDa Form Lyophilized or Liquid Concentration 1mg/ml immunogen KLH conjugated synthetic peptide derived from human HMX1 Lsotype IgG Purification affinity purified by Protein A Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol Storage Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. Product Detail background:
This gene encodes a transcription factor that belongs to the H6 family of homeobox proteins. This protein can bind a 5'-CAAG-3' core DNA sequence, and it is involved in the development of craniofacial structures. Mutations in this gene cause oculoauricular syndrome, a disorder of the eye and external ear. [provided by RefSeq, Oct 2009]
Function:
HMX1 acts as a transcriptional antagonist. It is part of the Hmx family of homeodomain proteins which are predominately expressed in discrete regions of developing sensory tissues.
Subcellular Location:
Nuclear
Similarity:
Belongs to the HMX homeobox family.
Contains 1 homeobox DNA-binding domain.
Database links:Entrez Gene: 396546 Chicken
Entrez Gene: 3166 Human
Entrez Gene: 15371 Mouse
Omim: 142992 Human
SwissProt: Q9DE09 Chicken
SwissProt: Q9NP08 Human
SwissProt: O70218 Mouse
Unigene: 104134 Human
Unigene: 358606 Mouse
Unigene: 24574 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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