Product Name	Anti-Speedy protein C/AF555
Chinese Name	AF555标记的快速周期蛋白C抗体
Alias	hSpy/Ringo C; Rapid inducer of G2/M progression in oocytes C; Rapid inducer of G2/M progression in oocytes, Xenopus, homolog of, C; RINGO C; Ringo2; SPDYC; SPDYC_HUMAN; speedy C; speedy homolog C; Speedy protein C; Speedy, Xenopus, homolog of, C.
Research Area	Cell biology  Cyclin  Epigenetics
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, )
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	33kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Speedy protein C
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: Promotes progression through the cell cycle via binding and activation of CDK1 and CDK2. Function: Promotes progression through the cell cycle via binding and activation of CDK1 and CDK2. Involved in the spindle-assembly checkpoint. Required for recruitment of MAD2L1, BUBR1 and BUB1 to kinetochores. Required for the correctlocalization of the active form of Aurora B in prometaphase. Subunit: Interacts with CDK1 and CDK2. Interacts with AURKB. Subcellular Location: Nucleus. Tissue Specificity: Expressed in a variety of tissues including bone marrow, kidney, small intestine, liver, placenta and testis. DISEASE: Expressed in a variety of tissues including bone marrow, kidney, small intestine, liver, placenta and testis. Similarity: Belongs to the Speedy/Ringo family. Database links: Entrez Gene: 387778 Human Omim: 614030 Human SwissProt: Q5MJ68 Human Unigene: 450642 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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