Product Name	Anti-JAKMIP3/AF555
Chinese Name	AF555标记的神经内分泌长卷曲螺旋蛋白2抗体
Alias	bA140A10.5; C10orf14; C10orf39; Jamip3; Janus kinase and microtubule interacting protein 3; NECC2; Neuroendocrine long coiled coil 2; Neuroendocrine long coiled coil protein 2; rCG_47434; RGD1307177; RP11-140A10.6; JKIP3_HUMAN
Research Area	Cell biology  Neurobiology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	(predicted: Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, )
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	98kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human JAKMIP3
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: JAKMIP3 is an 844 amino acid protein that belongs to the JAKMIP family. Localizing to the Golgi apparatus, JAKMIP3 is expressed in the central nervous system, as well as endocrine tissue, heart, testis and prostate. Existing as two alternatively spliced isoforms, the gene encoding JAKMIP3 maps to human chromosome 10q26.3 and mouse chromosome 7 F4. Spanning nearly 135 million base pairs, chromosome 10 makes up approximately 4.5% of total DNA in cells and encodes nearly 1,200 genes. Several protein-coding genes, including those that encode for chemokines, cadherins, excision repair proteins, early growth response factors (Egrs) and fibroblast growth receptors (FGFRs), are located on chromosome 10. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria Subcellular Location: Golgi apparatus Tissue Specificity: Specifically expressed in the CNS and endocrine tissues. Also detected in other tissues including heart,testis and prostate. Similarity: Belongs to the JAKMIP family. Database links: Entrez Gene: 282973 Human Entrez Gene: 74004 Mouse Entrez Gene: 365380 Rat Omim: 611198 Human SwissProt: Q5VZ66 Human SwissProt: Q5DTN8 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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