Product Name	Anti-Kinesin C2/AF555
Chinese Name	AF555标记的驱动蛋白家族成员C2抗体
Alias	KIF C2; KIFC 2; KIFC2; KIFC2 protein; KIFC2_HUMAN; Kinesin family member C2; Kinesin like protein KIFC2; Kinesin-like protein KIFC2.
Research Area	Cell biology  Signal transduction
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, Cow, Horse, Sheep, )
Applications	not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	90kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Kinesin C2
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: The kinesin superfamily proteins (KIFs) are microtubule-dependent molecular motors that transport membranous organelles and protein complexes in a microtubule- and ATP-dependent manner. Cells use KIFs to tightly control the direction, destination, and speed of transportation of a variety of important functional molecules, including mRNA. KIFC2 is 792 amino acid member of the C-terminal motor family specifically expressed in both the central and peripheral nervous systems in nonproliferative cells. KIFC2 accumulates at the proximal and distal sides of axons and is a minus-end-directed kinesin. KIFC2 localizes with some, but not all, axonally transported organelles. KIFC2 may be involved in retrograde axonal transport. Function: May play a role in microtubule-dependent retrograde axonal transport. May function as the motor for the transport of multivesicular body (MVB)-like organelles in dendrites. Subcellular Location: Cytoplasm; cytoskeleton. Similarity: Belongs to the kinesin-like protein family. Contains 1 kinesin-motor domain. Database links: Entrez Gene: 90990 Human Entrez Gene: 16581 Mouse Entrez Gene: 300053 Rat SwissProt: Q96AC6 Human SwissProt: O08672 Mouse Unigene: 528713 Human Unigene: 378950 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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