Product Name	Anti-Kv1.2/AF555
Chinese Name	AF555标记的电压门控钾通道Kv1.2抗体
Alias	Akr6a4; BK2; HBK5; HK4; HUKIV; Kca1 2; kcna2; KV1.2; MGC50217; Mk 2; MK2; NGK1; Potassium voltage gated channel shaker related subfamily member 2; Potassium voltage-gated channel subfamily A member 2; RBK2; Voltage gated potassium channel subunit Kv1.2. KCNA2_HUMAN
Research Area	Cardiovascular  Cell biology  Neurobiology  Channel protein  The cell membrane蛋白
Immunogen Species	Rabbit
Clonality	Polyclonal
React Species	Mouse,  (predicted: Human, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, )
Applications	ICC=1:50-200 IF=1:50-200  not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Molecular weight	57kDa
Form	Lyophilized or Liquid
Concentration	1mg/ml
immunogen	KLH conjugated synthetic peptide derived from human Kv1.2
Lsotype	IgG
Purification	affinity purified by Protein A
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
Storage	Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Product Detail	background: Kv1.2 mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which K(+) ions may pass in accordance with their electrochemical gradient. Kv1.2 binds PDZ domains of DLG1, DLG2 and DLG4. The N-terminus may be important in determining the rate of inactivation of the channel while the tail may play a role in modulation of channel activity and/or targeting of the channel to specific subcellular compartments. Function: Mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. Subunit: Heterotetramer of potassium channel proteins. Subcellular Location: Membrane; Multi-pass membrane protein Similarity: Belongs to the potassium channel family. Database links: Entrez Gene: 395117 Chicken Entrez Gene: 3737 Human Entrez Gene: 16490 Mouse Entrez Gene: 25468 Rat Omim: 176262 Human SwissProt: P16389 Human SwissProt: P63141 Mouse SwissProt: P63142 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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